Table of Contents

Part 1 Fundamentals of Cardiovascular Disease

1. Global Burden of Cardiovascular Disease

2. Heart Disease in Varied Populations

3. Ethics in Cardiovascular Medicine

4. Clinical Decision Making and Cost Effectiveness

5. Measurement and Improvement of Quality of Cardiovascular Care

6. Critical Evaluation of Clinical Trials

Part 2 Genetics and Personalized Medicine

7. Overview of Personalized Cardiovascular Medicine

8. Principles of Cardiovascular Genetics and Genomics

9. Drug Therapeutics and Personalized Medicine

10. Biomarkers, Proteomics and Metabolomics in Personalized medicine

Part 3 Evaluation of the Patient

11. The History and Physical Examination: An Evidence-Based Approach

12. Electrocardiography

Guidelines: Electrocardiography

13. Exercise Stress Testing

Guidelines: Exercise Stress Testing

14. Echocardiography

Guidelines- Appropriate Use Criteria: Echocardiography

15. The Chest Radiograph in Cardiovascular Disease

16. Nuclear Cardiology

Guidelines- Appropriate Use Criteria: Nuclear Cardiology

17. Cardiovascular Magnetic Resonance

Guidelines- Appropriate Use Criteria: Cardiovascular Magnetic Resonance

18. Cardiac Computed Tomography

Guidelines- Appropriate Use Criteria: Cardiac Computed Tomography

19. Cardiac Catheterization

20. Coronary Angiography and Intracoronary Imaging

Guidelines: Coronary Arteriography

Part 4 Heart Failure

21. Mechanisms of Cardiac Contraction and Relaxation

22. Pathophysiology of Heart Failure

23. Clinical Assessment and Heart Failure

24. Diagnosis and Management of Acute Heart Failure

25. Management of Heart Failure Patients with Reduced Ejection Fraction

Guidelines: Management of Heart Failure

26. Devices for Monitoring and Managing Heart Failure

27. Heart Failure with Normal Ejection Fraction

28. Surgical Management of Heart Failure

29. Assisted Circulation in the Treatment of Heart Failure

30. Cardiovascular Regeneration and Gene Therapy

31. Care of Patients with End-Stage Heart Disease

Part 5 Arrhythmias, Sudden Death, and Syncope

32. Genetic Bases of Cardiac Arrhythmias

33. Genesis of Cardiac Arrhythmias: Electrophysiological Considerations

34. Diagnosis of Cardiac Arrhythmias

Guidelines: Ambulatory Electrocardiographic and Electrophysiological Testing

35. Therapy for Cardiac Arrhythmias

36. Pacemakers and Implantable Cardioverter-Defibrillators

Guidelines: Cardiac Pacemakers and Cardioverter-Defibrillators

37. Specific Arrhythmias: Diagnosis and Treatment

38. Atrial Fibrillation: Clinical Features, Mechanisms, and Management Guidelines: Atrial Fibrillation

39. Cardiac Arrest and Sudden Cardiac Death

40. Hypotension and Syncope

Part 6 Preventive Cardiology

41. The Vascular Biology of Atherosclerosis

42. Risk Factors and the Prevention of Coronary Heart Disease

43. Systemic Hypertension: Mechanisms and Diagnosis

44. Systemic Hypertension: Therapy

Guidelines: Treatment of Hypertension

45. Lipoprotein Disorders and Cardiovascular Disease

46. Nutrition and Cardiovascular Disease

47. Exercise-Based, Comprehensive Cardiac Rehabilitation

48. Integrative Approaches to Management of Patients with Heart Disease

Part 7 Atherosclerotic Cardiovascular Disease

49. Coronary Blood Flow and Myocardial Ischemia

50. Approach to the Patient with Chest Pain

51. ST-Elevation Myocardial Infarction: Pathology, Pathophysiology, and Clinical Features

52. ST-Elevation Myocardial Infarction: Management

53. Unstable Angina and Non-ST Elevation Myocardial Infarction Acute Coronary Syndrome

54. Stable Ischemic Heart Disease

55. Percutaneous Coronary Intervention

56. Percutaneous Therapies for Structural Heart Disease in Adults

57. Diseases of the Aorta

58. Peripheral Arterial Diseases

59. Prevention and Management of Stroke

60. Endovascular Treatment of Noncoronary Obstructive Vascular Disease

61. Diabetes and the Cardiovascular System

Part 8 Diseases of the Heart, Pericardium, and Pulmonary Vasculature Bed

62. Congenital Heart Disease

63. Valvular Heart Disease

64. Cardiovascular Infections: Infective Endocarditis and Device Infections

65. The Dilated, Restrictive, and Infiltrative Cardiomyopathies

66. Hypertrophic Cardiomyopathy

67. Myocarditis

68. Chemical Cardiomyopathies

69. Cardiooncology: Cardiovascular Complications of Cancer Therapeutics

70. Cardiovascular Abnormalities in HIV-Infected Individuals

71. Pericardial Diseases

72. Traumatic Heart Disease

73. Pulmonary Embolism

74. Pulmonary Hypertension

75. Sleep Apnea and Cardiovascular Disease

Part 9 Cardiovascular Disease in Special Populations

76. Cardiovascular Disease in the Elderly

77. Cardiovascular Disease in Women

78. Pregnancy and Heart Disease

79. Exercise and Sports Cardiology

80. Perioperative Management in Noncardiac and Cardiac Surgery

Part 10 Cardiovascular Disease and Disorders of Other Organs

81. Endocrine Disorders and Cardiovascular Disease

82. Hemostasis, Thrombosis, Fibrinolysis, and Cardiovascular Disease

83. Rheumatic Fever

84. Rheumatic Diseases and the Cardiovascular System

85. Tumors Affecting the Cardiovascular System

86. Psychiatric and Behavioral Aspects of Cardiovascular Disease

87. Neurologic Disorders and Cardiovascular Disease

88. Interface Between Renal Disease and Cardiovascular Illness

89. Cardiovascular Manifestations of Autonomic Disorders

About the Author

Dr. Peter Libby is a cardiovascular medicine specialist at Brigham and Women's Hospital and Mallinckrodt Professor of Medicine at Harvard Medical School (HMS). Receiving his medical degree from the University of California, San Diego School of Medicine, he undertook a cellular physiology research fellowship at HMS. After a residency in internal medicine and a fellowship in cardiovascular disease, he became board certified in both. He is an editor of the leading cardiovascular medicine textbook, and the author of over 500 peer-reviewed publications, 575 reviews, chapters, etc. He has received funding from the American Heart Association (AHA) and National Institutes of Health, plus recognitions on four continents, including the AHA and American College of Cardiology's highest research awards, the Gold Medal of the European Society of Cardiology, the Anitschkow award from the European Atherosclerosis Society, the Ernst Jung Gold Medal for Medicine, and the Earl Benditt award for vascular biology.

Reviews

"This is a truly remarkable book, a phenomenal compendium of cardiovascular medicine is found within the covers of this book...It has matured into what is seemingly a comprehensive review of the speciality with the accent very much clinical care...without doubt this is a premium offering of an outstanding book for someone with a deep interest in cardiovascular medicine." (Review of 9th Edition)