Table of Contents

1. Metalloporphyrin Models for Cytochrome P-450.- 2. Comparison of the Peroxidase Activity of Hemeproteins and Cytochrome P-450.- 3. The Topology of the Mammalian Cytochrome P-450 Active Site.- 4. Cytochrome P-450 Reductase and Cytochrome b5 in Cytochrome P-450 Catalysis.- 5. Cytochrome P-450 Organization and Membrane Interactions.- 6. Comparative Structures of P-450 Cytochromes.- 7. Oxygen Activation and Transfer.- 8. Inhibition of Cytochrome P-450 Enzymes.- 9. Induction of Hepatic P-450 Isozymes: Evidence for Specific Receptors.- 10. Regulation of Synthesis and Activity of Cytochrome P-450 Enzymes in Physiological Pathways.- 11. Cytochrome P-450 Enzymes in Sterol Biosynthesis and Metabolism.- 12. Cytochrome P450cam and Other Bacterial P-450 Enzymes.- 13. The Crystal Structure of Cytochrome P450cam.- Appendix. Rat Hepatic Cytochrome P-450: Comparative Study of Multiple Isozymic Forms.