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Design and Analysis of Sequential Clinical Trials


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Table of Contents

Clinical Trials. Allocating Patients to Treatments. Measurement of Treatment Difference. The Design of a Sequential Trial Using the Boundaries Approach. The Analysis of a Sequential Trial. Alternative Approaches to the Design and Analysis of Sequential Clinical Trials. Prognostic Factors. The Comparison of More than Two Treatments. Implementation of Sequential Methods: Some Examples. References. Appendix. Index.

About the Author

John Whitehead is the author of The Design and Analysis of Sequential Clinical Trials, Revised, 2nd Edition, published by Wiley.


"...This book is clear, it provides many details and is well written..." (Statistical Methods in Medical Research, No.11, 2002)

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