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Drugs and the Liver


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Table of Contents

Part 1 - Understanding Liver Function; 1. Introduction to the Anatomy of the Liver; 2. Functions of the Liver; 3. Causes of Liver Disease and Dysfunction; 4. Assessing Liver Function; Part 2 - Principles of Drug Use in Liver Disease; 5. Pharmacokinetics of Drugs in Liver Disease; 6. Undesirable Side Effects; Part 3 - Putting the Theory into Practice; 7. Applying the Principles - introduction; 8. Introducing the Aide Memoire; 9. Scenario 1 Choice of Analgesia; 10. Scenario 2 Choice of Anti-emetic; 11. Scenario 3 Choice of Anti-hyperlipidaemic Agent; 12. Scenario 4 Choice of Hormone Replacement Therapy (HRT); 13. Scenario 5 Choice of Contraceptive; Appendix 1 - Detailed Description of the Patient Cases; Appendix 2 - The Blank Aide Memoire Form.


'For those pharmacists involved in medication reviews, interpretation of liver function test results is an essential part of the process. This book provides an excellent explanation of each parameter and the limitations of using the results alone when assessing the degree of liver function.'
Jackie Smith, a pharmaceutical advisor, Chemist and Druggist, October 2008 -- Jackie Smith * Chemist and Druggist *
'This book combines all pertinent issues relating to liver dysfunction and medication use in one reference. The authors and contributors have done an excellent job to make the book a practical tool that can be used by clinicians when making therapeutic choices rather than merely presenting pharmacokinetic principles and expected alterations in liver disease.'
Sharya Vaughan Bourdet, PharmD BCPS, The Annals of Pharmacotherapy Vol. 42, July/August 2008 -- Sharya Vaughan Bourdet * The Annals of Pharmacotherapy *
'The book is written primarily for pharmacist clinicians, but it serves as a useful review for anyone who has an interest in drug metabolism and liver function...the thorough but easy to understand review of the liver anatomy and function is a highlight. This is a good read for those who need to brush up on these topics.'
Patrick J. McDonnell, Temple University School of Pharmacy. Doody Enterprises, Inc. April 2008 -- Patrick J. McDonnell * Doody Enterprises *

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