Table of Contents

Genetics and immunology in inflammatory bowel diseases.- Inflammatory bowel disease genotypes and phenotypes.- Abnormalities of cytokine regulation in the inflammatory bowel diseases.- Dendritic cells — key players in inflammatory bowel disease.- Lipids and inflammatory bowel disease: microsomal triglyceride transfer protein — the new dimension?.- The intestinal epithelium and inflammatory bowel disease.- Evidence-based treatment in inflammatory bowel diseases.- Evidence-based therapy with aminosalicylates.- The practical use of steroids in inflammatory bowel disease.- Immunosuppressants: clinical use and molecular mechanism of action.- Biologicals: old and new ones.- Difficult cases in inflammatory bowel diseases.- Management of extraintestinal disease in inflammatory bowel disease.- Innate immunity — microbial products.- Immunomodulatory properties of the gut microflora.- Defensins and other antimicrobial mediators.- Post-infectious irritable bowel syndrome: role of inflammation and gut flora.- Gut-liver interactions — basic and clinical aspects.- The liver and its contribution to induction of oral tolerance.- Molecular regulation of lymphocyte homing between the liver and the gut.- Modern concepts of coeliac disease pathogenesis.- Hepatobiliary manifestations in inflammatory bowel disease.- Primary biliar cirrhosis, cholestasis and autoimmune liver disease.- Primary biliary cirrhosis and biliary destruction: 2005; a liver odyssey.- Primary biliary cirrhosis: clinical aspects.- Molecular mechanisms of cholestasis.- Primary sclerosing cholangitis, alcoholic steatohepatitis, non-alchoholic steatohepatitis.- Basic concepts in primary sclerosing cholangitis — what can we learn from studies of its genetic basis.- Clinical concepts in primary sclerosingcholangitis.- Alcoholic liver diseases.- Should non-alcoholic fatty liver disease be treated differently in elderly patients?.- Liver failure and transplantation.- Acute liver failure — mechanisms of liver cell destruction.- Clinical management of acute liver failure.- Liver and bowel transplantation in 2005.- Established and novel methods for treating inflammatory diseases by inhibition of cytokines.