Table of Contents

Number of Liganded Molecules.

Affinities: From a Site Perspective.

Affinities: From a Stoichiometric Perspective.

Affinities: From a Ghost-Site Perspective.

Facts and Fantasies from Graphical Analyses.

Numerical Evaluations of Stoichiometric Binding Constants.

Affinity Profiles.

Thermodynamic Perspectives.

Forces of Interaction.

Molecular Scenarios.

Appendices.

Index.

About the Author

IRVING M. KLOTZ, PhD, is Morrison Professor Emeritus in the Departments of Chemistry and of Biochemistry, Molecular Biology, and Cell Biology at Northwestern University. He has published books on thermodynamics and biochemical energetics, as well as many research papers on ligand-receptor interactions and the structure and function of proteins.