1. Fundamentals of Neuropharmacology1. Basic Principles of Neuropharmacology2. Cellular Basis of Communication3. Synaptic Transmission4. Signal Transcuction in the Brain2. Neural Substrates of Drug Action5. Excitatory and Inhibitory Amino Acids6. Monoamines, Acetylcholine, and Orexin7. Neuropeptides8. Atypical NeurotransmittersNeuropharmacology of Neural Systems and Disorders9. Autonomic Nervous System10. Neural and Neuroendocrine Control of Internal Mileau11. Pain 12. Neuroinflammation13. Sleep and Arousal14. Cognitive Function and Behavior15. Mood and Emotion16. Reinforcement and Addiction17. Schizophrenia and Other Psychoses18. Neurodegeneration19. Seizures20. Stroke and Migraine
Eric J. Nestler, MD is Professor and Chairman of the Department of
Psychiatry and the Center for Basic Neuroscience at the
Southwestern Medical School, Graduate School of Biomedical
Sciences, Dallas Texas. He is also the Lou and Ellen McGinley
Distinguished Chair in Psychiatric Research. The goal of Dr.
Nestler's research is to better understand the ways in which the
brain responds to repeated perturbations under normal and
pathological conditions. A major focus of the research is drug
addiction: to identify molecular changes that drugs of abuse
produce in the brain to cause addiction, and to characterize the
genetic and environmental factors that determine individual
differences in the ability of the drugs to produce these changes. A
related interest is to understand the contribution of the brain's
reward regions to the regulation of normal mood as well as the
abnormalities in mood and motivation seen in depression. Dr.
Nestler has authored or edited 5 books, and has authored or
co-authored 180 original research articles and 90 review articles
and book chapters. He currently mentors seven post-doctoral fellows
and six graduate students. He has trained 27 post-doctoral
researchers, eight research track residents, and ten graduate
students. Dr. Nestler is the recipient of numerous awards and
honors, including the Pfizer Scholars Award (1987), Sloan Research
Fellowship (1987), McKnight Scholar Award (1989), Efron Award of
the American College of Neuropsychopharmacology (1994), and Pasarow
Foundation Award for Neuropsychiatric Research (1998). He has
served on the Board of Scientific Counselors of the National
Institute on Drug Abuse, and currently serves on the Scientific
Advisory Boards of the National Alliance for Research in
Schizophrenia and Depression and of the National Alliance for
Autism Research. Dr. Nestler is also a member of the National
Advisory Mental Health Council, the Council of the Society for
Neuroscience, and the Council of the American College of
Neuropsychopharmacology
Steven E. Hyman, MD is Provost of Harvard University and Professor
of Neurobiology at Harvard Medical School, Boston, MA. From 1996 to
2001, he served as Director of the National Institute of Mental
Health (NIMH), the component of the US National Institutes of
Health charged with generating the knowledge needed to understand
and treat mental illness. Before serving as Director of NIMH, Dr.
Hyman was Professor of Psychiatry at Harvard Medical School,
Director of Psychiatry Research at Massachusetts General Hospital ,
and the first faculty Director of Harvard University's Mind, Brain,
and Behavior Initiative. In the laboratory he studied the molecular
biology of neurotransmitter action. Dr. Hyman is a member of the
Institute of Medicine of the National Academy of Sciences and of
the American Academy of Arts and Sciences. He is currently serves
as Editor of the Annual Review of Neuroscience. He received his BA
from Yale College in 1974 summa cum laude, and his MA from the
University of Cambridge in 1976, which he attended as a Mellon
fellow studying the history and philosophy of science. He earned
his MD from Harvard Medical School in 1980.
Robert C. Malenka, MD, PhD is Pritzker Professor of Psychiatry &
Behavioral Sciences at Stanford University, Palo Alto, CA. He is a
fellow of the American Academy of Arts and Sciences, a member of
the Institute of Medicine of the National Academies and an
Associate of the Neurosciences Research Program. He has won several
awards including the International Prize in Neuroscience, the
Distinguished Alumni Award from Stanford University and the Daniel
Efron Award from the American College of Neuropsychopharmacology. A
major goal of his laboratory is to elucidate both the specific
molecular events that are responsible for the triggering of these
various forms of synaptic plasticity and the exact modifications in
synaptic proteins that are responsible for the observed,
long-lasting changes in synaptic efficacy.
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