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Netter's Neurology


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Table of Contents

I. Neurologic Examination Chapter 1. Clinical Neurologic Evaluation 2 Chapter 2. Cognitive and Language Evaluation 40 II. Neuro-ophthalmology Chapter 3. Retina and Optic Nerve 54 Chapter 4. Optic Chiasm, Optic Tract, Lateral Geniculate Nucleus, and Optic Radiations 64 Chapter 5. Primary Visual Cortex 72 Chapter 6. Cranial Nerve III: Oculomotor 77 Chapter 7. Cranial Nerve IV: Trochlear 85 Chapter 8. Cranial Nerve VI: Abducens 89 III. Cranial Nerves Chapter 9. Cranial Nerve I: Olfactory 96 Chapter 10. Cranial Nerve V: Trigeminal 101 Chapter 11. Cranial Nerve VII: Facial 112 Chapter 12. Cranial Nerve VIII: Vestibular 126 Chapter 13. Cranial Nerve VIII: Auditory 134 Chapter 14. Cranial Nerve IX, Glossopharyngeal, and Cranial Nerve X, Vagus: Swallowing 143 Chapter 15. Cranial Nerve X, Vagus: Voice Disorders 153 Chapter 16. Cranial Nerve XI: Spinal Accessory 157 Chapter 17. Cranial Nerve XII: Hypoglossal 163 IV. Headache Chapter 18. Primary and Secondary Headache 170 V. Cerebrovascular Disorders Chapter 19. Arterial Supply to the Brain and Meninges 188 Chapter 20. Ischemic Stroke 195 Chapter 21. Endarterectomy for Extracranial Carotid Artery Atherosclerosis 218 Chapter 22. Cerebral Venous Thrombosis 223 Chapter 23. Intracerebral Hemorrhage 234 Chapter 24. Cerebral Aneurysms and Subarachnoid Hemorrhage 248 VI. Epilepsy and Syncope Chapter 25. Epilepsy and Syncope 264 Chapter 26. Surgical Treatments for Epilepsy 281 VII. Sleep Disorders Chapter 27. Sleep Disorders 288 VIII. Disorders of Consciousness Chapter 28. Coma 296 Chapter 29. Increased Intracranial Pressure and Cerebral Herniation 307 Chapter 30. Brain Death 316 IX. Memory and Cognitive Disorders Chapter 31. Acute Cognitive and Behavioral Disorders 322 Chapter 32. Alzheimer Disease 327 Chapter 33. Dementia With Lewy Bodies 347 Chapter 34. Frontotemporal Dementia 351 Chapter 35. Vascular Dementia 356 Chapter 36. Transmissible Spongiform Encephalopathy 360 X. Psychiatric Disorders Chapter 37. Major Depression 366 Chapter 38. Bipolar Disorder 369 Chapter 39. Schizophrenia 372 Chapter 40. Obsessive-Compulsive Disorder 375 Chapter 41. Panic Disorder 378 Chapter 42. Dysthymia 381 Chapter 43. Borderline Personality Disorder 384 Chapter 44. Attention Deficit Disorder 387 Chapter 45. Drug and Alcohol Abuse 390 Chapter 46. Delirium 399 XI. Movement Disorders Chapter 47. Parkinson Disease 402 Chapter 48. Atypical Parkinsonian Syndromes 414 Chapter 49. Tremors 422 Chapter 50. Medication-Induced Movement Disorders 432 Chapter 51. Dystonia 438 Chapter 52. Myoclonus 447 Chapter 53. Chorea 453 Chapter 54. Tic Disorders 460 Chapter 55. Wilson Disease 466 Chapter 56. Psychogenic Movement Disorders 472 Chapter 57. Surgical Treatments for Movement Disorders 475 XII. Gait Disorders and Dizziness Chapter 58. Gait Disorders 480 XIII. Myelopathies Chapter 59. Anatomical Aspects of Myelopathies 492 Chapter 60. Acute Myelopathies 503 Chapter 61. Chronic Myelopathies 514 XIV. Multiple Sclerosis and Other Demyelinating Disorders Chapter 62. Multiple Sclerosis and Acute Disseminated Encephalomyelitis 538 XV. Infectious Disease Chapter 63. Bacterial Meningitis 560 Chapter 64. Parameningeal Infections 566 Chapter 65. Neurosyphilis 570 Chapter 66. Viral Infections of the Nervous System 574 Chapter 67. Tuberculosis of Brain and Spine 583 Chapter 68. Infections in Immunocompromised Hosts 586 Chapter 69. Tetanus 594 Chapter 70. Poliomyelitis 597 XVI. Neuro-oncology Chapter 71. Neuro-oncology Differential Diagnosis 604 Chapter 72. Malignant Brain Tumors 611 Chapter 73. Benign Brain Tumors 622 Chapter 74. Spinal Cord Tumors 635 XVII. Trauma to the Brain and Spinal Cord Chapter 75. Brain Trauma 644 Chapter 76. Trauma of the Spine and Spinal Cord 658 XVIII. Radiculopathies Chapter 77. Cervical Radiculopathy 672 Chapter 78. Lumbar Radiculopathy 679 Chapter 79. Lumbar Spinal Stenosis 691 Chapter 80. Rheumatologic, Functional, and Psychosomatic Back Pain 694 XIX. Plexopathies Chapter 81. Brachial Plexus and Brachial Plexopathies 700 Chapter 82. Lumbosacral Plexopathies 708 XX. Mononeuropathies Chapter 83. Overview of Mononeuropathies 716 Chapter 84. Mononeuropathies Presenting With Upper Extremity Symptoms 726 Chapter 85. Mononeuropathies Presenting With Shoulder Pain and Weakness 741 Chapter 86. Mononeuropathies Presenting With Lower Extremity Weakness 746 Chapter 87. Primary Sensory Neuropathies of the Lower Extremity 757 XXI. Motor Neuron Disorders Chapter 88. Overview of Motor Neuron Disease 764 Chapter 89. Motor Neuron Disease Presenting in the Limbs With Lower Motor Neuron Features 777 Chapter 90. Primary Lateral Sclerosis: Motor Neuron Disease Presenting With Upper Motor Neuron Features in the Limbs 783 Chapter 91. Motor Neuron Disease: Bulbar, Head Drop, and Ventilatory Presentations 789 Chapter 92. Stiff Person Syndrome 794 XXII. Polyneuropathies and Autonomic Disorders Chapter 93. Overview of Peripheral Nerve Disease 800 Chapter 94. Length-Dependent Polyneuropathy 808 Chapter 95. Acquired Demyelinating Polyradiculoneuropathies: Guillain-Barre Syndrome and Chronic Inflammatory Demyelinating Polyradiculoneuropathy 818 Chapter 96. Multifocal Neuropathies 827 Chapter 97. Sensory Neuropathy and Neuronopathy 834 Chapter 98. Leprosy (Hansen Disease) 839 Chapter 99. Disorders of the Autonomic Nervous System 843 XXIII. Neuromuscular Transmission Disorders Chapter 100. Neuromuscular Junction Anatomy and Physiology 850 Chapter 101. Lambert-Eaton Myasthenic Syndrome 858 Chapter 102. Myasthenia Gravis 864 XXIV. Myopathies Chapter 103. Overview of Muscle Disease 872 Chapter 104. Acute or Subacute Proximally Predominant or Generalized Myopathies Presenting With Weakness 884 Chapter 105. Myopathies: Chronic Proximally Predominant or Generalized Weakness 892 Chapter 106. Distal Predominant Myopathies 906 Chapter 107. The Channelopathies: Myopathies Presenting With Episodic Weakness 909 Chapter 108. Myopathies Presenting With Exercise Intolerance 914 Index 923

About the Author

Dr. H. Royden Jones was Chair of the Department of Neurology at Lahey Hospital and Medical Center, Burlington, Massachusetts; Director of the Electromyography Laboratory at Boston Children's Hospital; and Clinical Professor of Neurology at Harvard Medical School. Dr. Jones completed residencies in Internal Medicine and Neurology and a fellowship in neurological physiology at the Mayo Clinic. He served over 3 years in the United States Army as Chief of Neurology at 5th General Hospital, Bad Cannstatt, Germany. Dr. Jones was Board certified in neurology, clinical neurophysiology, and neuromuscular medicine. Upon completion of his training he joined the Lahey Clinic in 1972. In 1977 he also joined the neurology department at Boston Children's Hospital, founding the electromyography laboratory in 1979. Pediatric EMG became his major clinical research interest. Dr. Jones was co-editor of three major textbooks on childhood clinical neurophysiology and neuromuscular disorders. He was a co-founder of the biennial International Paediatric EMG Conference based at Great Ormond Street Children's Hospital, London, England. Recognized as one of the top neurologists in the U.S., Dr. Jones was an author and editor of several Netter publications including two editions of Netter's Neurology, The Netter Collection of Medical Illustrations: Nervous System, Volume 7, Part I (Brain) and Part II (Spinal Cord and Peripheral Motor and Sensory Systems), 2nd Editions (volumes in the Netter Green Book Collection). Dr. Jones authored and edited several other Netter publications and contributed over 200 peer-reviewed papers and book chapters. Dr. Jones served 8 years as a director of the American Board of Psychiatry and Neurology, becoming Chair of its Neurology Council in 2004. In 2007 he received the Distinguished Physician Award from the American Association of Neuromuscular and Electrodiagnostic Medicine. Lahey Clinic's Medical Staff Association recognized Dr. Jones in 2010 with its highest honor-the Frank Lahey Award for commitment to the values of Dr. Frank Lahey: respect, teamwork, excellence, commitment to personal best." Dr. Jones was named Outstanding Teacher in Pediatric Neurology 2012 - 2013 by the Department of Neurology, Boston Children's Hospital, Harvard Medical School. He also received an award in recognition of his many years of dedicated teaching at Tufts University School of Medicine.


The text is sufficiently broad as to retain its relevance for practicing general physicians, while written with sufficient clarity as to attract students with little knowledge of the subject.
-Muscle & Nerve Sept 2005

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