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Neurologic Localization and Diagnosis
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Table of Contents

?Part 1. Approach to Neurologic Diagnosis.

Chapter 1.1. Overview of Neurologic Diagnosis

Approaches and why we need more than one.

Algorithmic diagnosis

Syndromic diagnosis

Differential diagnosis

Role of venue in diagnostic approach

Mistakes we make in diagnosis.

Chapter 1.2. Taking a History

Overview and organization

Preparing for the encounter

Chief complaint

History of present illness

Past medical and surgical history

Medication history

Family history

Review of systems

Social history

Chapter 1.3. The Neurologic Exam

Chapter 1.4. The Medical Exam in Neurologic Patients

Chapter 1.5. Synthesis of the Assessment and Plan

Chapter 1.6. Documenting Our Findings.

Part 2. Essentials of Clinical Neuroanatomy.

Chapter 2.1. Overview

Chapter 2.2. Cerebral Hemispheres

Chapter 2.3. Brainstem and Cerebellum

Chapter 2.4. Spinal cord

Chapter 2.5. Peripheral Nerves, Neuromuscular Junction and Muscle

Part 3. Localization by Dysfunction.

Chapter 3.1. Mental Status

Chapter 3.2. Cranial Nerve

Chapter 3.3. Motor.

Chapter 3.4. Sensory

Chapter 3.5. Coordination

Chapter 3.6. Gait

Chapter 3.7. Reflex Abnormalities

Chapter 3.8. Pain

Part 4. Localization by Anatomy.

Chapter 4.1. Cerebrum

Chapter 4.2. Cerebellum

Chapter 4.3. Brainstem and Cranial Nerves

Chapter 4.4. Spinal Cord

Chapter 4.5. Nerve Roots, Plexus, and Peripheral Nerves

Chapter 4.6. Neuromuscular Junction and Muscle

Chapter 4.7. Multi-System Disorders

Part 5. Diagnosis of Suspected Disorders.

Chapter 5.1. Disorders of Mental Status

Chapter 5.2. Speech and Language Disorders

Chapter 5.3. Stroke and other Vascular Disorders

Chapter 5.4. Seizure Disorders

Chapter 5.5. Neuromuscular Disorders

Chapter 5.6. Headache

Chapter 5.7. Movement Disorders

Chapter 5.8. Autoimmune Disorders

Chapter 5.9. Disorders of the Visual System

Chapter 5.10. Vestibular and Related Disorders

Chapter 5.11. Tumors with Neurologic Involvement

About the Author

Dr. Eli Zimmerman is an Assistant Professor of Neurology at Vanderbilt University Medical Center. He has multiple clinical and educational roles. Clinically, he sees vascular neurology patients in the inpatient and outpatient settings, as well as via teleneurology. He also serves as the Department of Neurology's Director of Medical Student Education, directs the Vascular Neurology fellowship, and teaches over 200 medical students each year in his leadership of courses in the medical school. He has won multiple teaching awards at Vanderbilt, including the Shovel Award in 2019, awarded by the graduating medical school class to the faculty member who had the most meaningful impact on their medical education. Martin A. Samuels, MD, FAAN, MACP, DSc (hon), is Professor of Neurology at Harvard Medical School and winner of the institution's first Faculty Prize for Excellence in Teaching. He is the Neurologist-in-Chief at Brigham and Women's Hospital, Boston, and former Director of the Harvard-Longwood Neurology Training Program. Dr. Samuels is an internationally renowned teacher-clinician, a premier diagnostician, and a leading authority on the interface between neurology and general medicine. His major fields of expertise include neurocardiology, neurohematology, neurogastroenterology, neurohepatology, neuronephrology, and the neurologic aspects of organ transplantation. He has edited several seminal neurology textbooks, developed a definitive instructional video on clinical neurology for practicing physicians, and authored numerous articles and book chapters. He is the 2006 recipient of the AB Baker Award for Lifetime Achievement in Neurologic Education. Dr. Samuels was the Founding Editor of NEJM Journal Watch Neurology in 1999 and was Editor-in-Chief from 1999 to 2010. Dr. Howard Kirshner is a professor of Neurology, Psychiatry, and Hearing and Speech Sciences. He also holds the positions of vice chairman for the Department of Neurology, director of the Vanderbilt Stroke Center, consultant at the Vanderbilt Stallworth Rehabilitation Hospital, and consulting neurologist at Williamson Medical Center. Dr. Kirshner is board certified in Neurology, Vascular Neurology, and Behavioral Neurology and Neuropsychiatry Dr. Karl Misulis is a neurologist at Vanderbilt University Medical Center, specializing in Hospital Neurology. After a fellowship in neurophysiology, he joined the Vanderbilt faculty practicing general neurology and researching nerve regeneration and brain tumor biology.Dr. Misulis transitioned to West Tennessee Healthcare where he was a hospital neurologist and Chief Medical Information Officer, while retaining his faculty appointment at Vanderbilt. He has returned to full-time practice at Vanderbilt University Hospital as Professor of Clinical Neurology and Director of the Neurology Hospitalist service. He has a secondary appointment as Professor of Clinical Biomedical Informatics. Dr. Misulis is board certified in Neurology by the American Board of Psychiatry and Neurology, certified in Clinical Informatics by the American Board of Preventative Medicine, and certified in EEG by the American Board of Clinical Neurophysiology.He has received numerous awards including being listed in Best Doctors for many years, Doctor of the Year at West Tennessee Healthcare in 2011.Dr. Misulis has published 19 books, with his 20th soon to be released and a 21st in preparation. He has taught medicine around the world, working directly with physicians on three continents, and lecturing on six.

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