1. Single Cell Oils for the 21st Century
2. Arachidonic Acid-Producing Mortierella alpina: Creation of
Mutants, Isolation of the Related Enzyme Genes, and Molecular
Breeding
3. Metabolic Engineering of an Oleaginous Yeast for the Production
of Omega-3 Fatty Acids
4. Development of a Docosahexaenoic Acid Production Technology
Using Schizochytrium: Historical Perspective and Update
5. Arachidonic Acid: Fermentative Production by Mortierella
Fungi
6. Production of Single Cell Oils by Dinoflagellates
7. Alternative Carbon Sources for Heterotrophic Production of
Docosahexaenoic Acid by the Marine Alga Crypthecodinium cohnii
8. Production of Eicosapentaenoic Acid Using Heterotrophically
Grown Microalgae
9. Downstream Processing, Extraction, and Purification of Single
Cell Oils
10. Searching for Polyunsaturated Fatty Acid-Rich Photosynthetic
Microalgae
11. Carotenoid Production Using Microorganisms
12. Survey of Commercial Developments of Microalgae as Biodiesel
Feedstock
13. Algae Oils for Biofuels: Chemistry, Physiology, and
Production
14. Production of Lipids for Biofuels Using Bacteria
15. Safety Evaluation of Single Cell Oils and the Regulatory
Requirements for Use as Food Ingredients
16. Nutritional Aspects of Single Cell Oils: Applications of
Arachidonic Acid and Docosahexaenoic Acid Oils
17. Recent Developments in the Human Nutrition of Polyunsaturated
Fatty Acids from Single Cell Oils
18. Applications of Single Cell Oils for Animal Nutrition
19. Applications of Single Cell Oils for Aquaculture
20. Future Development of Single Cell Oils
Covers the essential information providing details of the production of all the major SCOs, their extraction, purification, applications and safety evaluations
Professor Zvi Cohen received hs PhD from the Weizmann Institute of
Science in 1978. He is a member of the Blaustein Institute of
Desert Research in Ben Gurion University since 1981 and is the
incumbent of the Maks and Rochelle Etingin professorial chair in
Desert Research. His research involves the physiology,
biochemistry, molecular biology and biotechnology of PUFA
production in microalgae. Professor Cohen serves on the editorial
board of Annals of Microbiology and Biotechnology Letters, is the
editor of Chemicals from Microalgae and coeditor (with Colin
Ratledge) of Single Cell Oils. After gaining his PhD from
Manchester University and a four-year spell as a post-doc in
Trinity College, Dublin, Colin joined Unilever at their research
laboratories at Colworth House in the UK. It was here that he was
introduced to the pleasures of working with microbial lipids and of
trying to produce something commercially useful out of them.
However, the plug was pulled on the project and Colin decided to
return to the safer environment of academic research and joined the
teaching staff of the Department of Biochemistry at the University
of Hull in 1967. And here he has spent the rest of his career,
being promoted through the ranks until he was given a personal
professorial chair in 1983. Colin’s research work with microbial
lipids began to take off when he realised that nothing was known,
in biochemical terms, as to how some microorganism were able to
produce copious amounts of lipid in their cells whilst others
completely failed to do so. Work on the biochemistry of lipid
accumulation in yeasts and fungi was the main focus of much of the
research that was carried out at Hull. Work that was helped by many
research students, post-docs and dedicated technicians plus
government and EU grants and considerable support from industry who
began to take increasing interests as to what microorganisms might
be able to achieve in the way of producing desirable edible oils.
It was during this time that the terms were coined of 'Single Cell
Oils' and also 'oleaginous microorganisms’, both of which seem to
have been accepted as part of the glossary of lipids. The very
first commercial single cell oil was produced in 1985 as a result
of research work carried out at Hull; this was an oil rich in
?-linolenic acid (GLA) being produced by the fungus, Mucor
circinelloides. The large-scale process was developed by J & E
Sturge at Selby, North Yorkshire, using their expertise with fungi
as they were major producers of citric acid using Aspergillus
niger. Production was at the 220 m3 level and, when production
ceased in 1990, some 50 tons of GLA-SCO had been produced, all used
for human consumption. His work has been recognised by the receipt
of several awards, including the highly prestigious Stephen Chang
Award from AOCS in 2011. He has been visiting professor at a number
of universities including National University of Malaysia,
Polytechnic University Hong Kong, Ben Gurion University Israel and
Jiangnan University, China. Colin’s research work continued to
explore the finer details of lipid biosynthesis and accumulation in
both yeasts and fungi gradually building up a reasonable, but by no
means complete, picture as to what was going on in the oleaginous
microorganisms to allow them to accumulate so much lipid. In all,
he has published over 300 scientific papers and reviews plus being
writer and editor of 18 books.
Colin officially retired in 2004 but has continued to be active in
research and also with various editing roles including being
Associate Editor for Lipids, editorial advisor for Lipid Technology
and Editor in Chief of Biotechnology Letters. He also continues to
be a consultant for a number of companies involved in various
aspects of SCO production. Dept of Microbial Biochemistry,
University of Hull, Hull HU6 7RX, U.K.
Ask a Question About this Product More... |